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PINK1 peptide

Serine/threonine-protein kinase PINK1, mitochondrial
BRPK
PTEN-induced putative kinase protein 1
Gene name: PINK1
PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease. It protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.

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€238.00
Available
Ref : 00105458

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Product Code pep50039
Name PINK1
Print datasheet
Product type Peptides
Target Specificity Used as a blocking peptide for pab50180. This peptide is specific for pab50180.
Species Human, Mouse, Rat
Labelling None
Antibody / Antigen pab50180
Appearance Liquid
Conc. / Activity 1 mg/ml
Constituents Peptide dissolved in dH2O. Contains no BSA.
Preservatives None
Storage Store at -80C. Avoid freeze-thaw cycles.
Uniprot ID Q9BXM7
Gene ID 65018
Description WB
Research areas Autophagy,Cancer,Cell death,Disease-related biomarkers,Kinases and phosphatases,Signal transduction
Print datasheet

PINK1 peptide

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