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PINK1 antibody

Serine/threonine-protein kinase PINK1, mitochondrial
PTEN-induced putative kinase protein 1
Gene name: PINK1
Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids.Malfunctions in this contribute to many human cancers.PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers.It is found in the mitochondria and its homozygous C-terminus mutation has beenimplicated in the early development of Parkinson's disease.

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Ref : 00036102

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Product Code pab50180
Immunogen An N-terminal region synthetic peptide made to the human PINK1 protein sequence (between residues 1-50).
Target Specificity Reacts with human, mouse and rat PINK1.
Name Pink1
Uniprot ID Q9BXM7
Gene ID 65018
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents Tris-citrate, phosphate, (pH 7-8) buffer
Preservatives NaN3 0.1%
Storage Store at 4°C. Do not freeze.
Applications Western Blot
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (1:500)
Research areas Autophagy,Cancer,Cell death,Disease-related biomarkers,Kinases and phosphatases
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WB - PINK1 antibody<br/>(pab50180)<br/>Anti-Pink1 antibody WB staining of 2. MES cell Mitochondria (20 ug). 3. MES cytosol (20 ug). 4. MES nuclear (20 ug) as negative control. 5. Purified human cytochrome C (0.1 ug) as PINK1 negative control.

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