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PARK7 / DJ-1 (aa177-189) antibody

Protein DJ-1
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

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€360.00
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Ref : 00015060

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Product Code pab70048
Immunogen Synthetic peptide from human PARK7 / DJ-1 (aa177-189).
Target Specificity Reacts with aa 177-189 of human PARK7 protein. Cross reacts with proteins from African green monkey, Chimpanzee and Zebrafish.
Name PARK7 / DJ-1
Uniprot ID Q99497
Gene ID 11315
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Monkey, Zebrafish
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents K phosphate 20 mM, NaCl 150 mM, pH 7.2
Preservatives NaN3 0.01%
Storage Store vial at -20 C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20 C or below. Avoid cycles of freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA (1/10000 - 1/50000), IHC - P (2.5 µg/ml), WB (1/500 - 1/2000)
Research areas Autophagy,Disease-related biomarkers,Inflammation,Neurology
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IHC : PARK7 / DJ-1 (aa177-189) antibody<br/>(pab70048)<br/>Anti-PARK7 / DJ-1 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, <br/>paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab70048 concentrati

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