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PARK7 / DJ-1 (aa167-189) antibody

Protein DJ-1
Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.

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Ref : 00019325

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Product Code pab72052
Immunogen Synthetic peptide from residues 167-189 (AIVEALNGKEVAAQVKAPLVLKD) of human PARK7 (DJ-1)
Target Specificity Reacts with PARK7 (DJ-1) from human, gorilla, gibbon. May cross reacts with protein from monkey, horse, rabbit.
Name PARK7 / DJ-1
Uniprot ID Q99497
Gene ID 11315
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Monkey
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage +4°C or -20°C, Avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (10 µg/ml), WB (1:500 - 1:1000)
Research areas Autophagy,Cancer,Disease-related biomarkers,Inflammation,Neurology
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IHC : PARK7 / DJ-1 (aa167-189) antibody<br/>(pab72052)<br/>Anti-PARK7 / DJ-1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab72052 concentration 10 µ

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