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P2RX7 / P2X7 (aa13-26) antibody

P2X purinoceptor 7, P2X7, ATP receptor, P2Z receptor, Purinergic receptor
MGC20089, P2X receptor 7, P2X7, P2X7 purinoceptor
Gene names: P2RX7
Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.

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Ref : 00021405

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Product Code pab73132
Immunogen Synthetic peptide YETNKVTRIQSMNY-C from the N-terminus (aa13-26) of human P2RX7 / P2X7 (NP_002553.2). Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Hamster, Pig (100%), Monkey, Mouse, Rat, Guinea pig (93%), Elephant, Panda, Dog, Rabbit (86%).
Target Specificity Reacts with P2RX7 from human, hamster, pig. Predicted to cross react with monkey, mouse, rat, guinea pig.
Name P2RX7 / P2X7
Uniprot ID Q99572
Gene ID 5027
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Goat
Species Human, Hamster, Porcine
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Antigen affinity purified
Constituents TBS, pH 7.3, BSA 0.5%
Preservatives NaN3 0.02%
Storage Store at -20°C. Minimize freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ELISA (1:16000)
IHC-P (3.75 µg/ml)
WB (1 - 3 µg/ml)
Research areas Immunology,Ion channels
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IHC - P2RX7 / P2X7 (aa13-26) antibody<br/>(pab73132)<br/>Anti-P2RX7 / P2X7 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 µg/ml.

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