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Octamer-binding protein 4 (Oct-4) antibody

POU domain, class 5, transcription factor 1
Octamer-binding protein 3 (Oct-3)
Octamer-binding protein 4 (Oct-4)
Octamer-binding transcription factor 3 (OTF-3)
Gene name: POU5F1, OCT3, OCT4, OTF3
Stem cells are crucial ingredients in the progressive restriction of cellular developmental capacity during mammalian embryogenesis. Until recently, only embryonic stem cells (ESC)had been shown to exhibit the potential to differentiate into cells of the all three germ layers. However, adult stem cells (ASC) can regain pluripotency (potential to differentiate into various lineages) if transferred from one stem-cell microenvironment into another.The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.

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Product Code pab50208
Immunogen Synthetic peptide made to an internal portion of the human OCT4 protein sequence (between residues 100-200)
Target Specificity Reacts with Oct-4 protein from human, mouse, rat and primate. Predicted to cross react with bovine (93%), feline (93%), porcine (93%).
Name Octamer-binding protein 4 (Oct-4)
Uniprot ID Q01860
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Monkey
Labelling None
Appearance Liquid
Conc. / Activity 0,85 mg/ml
Form Purified
Constituents Tris-glycine, NaCl 150mM buffer
Preservatives NaN3 0.05%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Immunofluorescence, Immunocytochemistry, Flow Cytometry
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 2 µg/ml
- FC: 1:50-1:200
-ICC/IF; 1:50-1:200
Research areas Developmental biology,Neurology,Nuclear signaling,Stem cells
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Octamer-binding protein 4 (Oct-4) antibody

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