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Noggin antibody

Gene name: NOG
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor.Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

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€335.00
Available
Ref : 00036427

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Product Code pab51096
Immunogen Synthetic peptide comprising residues 156-170 [PVLYAWNDLGSRFWP] of the human Noggin protein
Target Specificity Reacts with Noggin from human, mouse and rat.
Name Noggin
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/1 000 to 1/2 000
Research areas Developmental biology,Neurology
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Noggin antibody

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