Close Forward an order
By clicking this button, you can send a message to your purchasing manager to ask her/him to order this product. All information needed about our company and the product will be automatically attached. You will also have the opportunity to ask us for more information about the product. If so, your request will be forwarded to our technical service.

Captcha

* Required Fields

Back to products list

Netrin receptor UNC5B antibody

Protein unc-5 homolog 2
Protein unc-5 homolog B
p53-regulated receptor for death and life protein 1
Gene name : UNC5B, P53RDL1, UNC5H2
Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity

If you want to order offline

orders@covalab.com - tel: +33 (0) 437 654 230 - fax: +33 (0) 437 289 416

Price From: €165.00
Available
Ref : 00014119

* Required Fields

Product Code pab0700-P
Immunogen UNC5B human recombinant protein
Target Specificity Reacts with human, mouse, rat UNC5B.
Name Netrin receptor UNC5B
Uniprot ID Q8IZJ1
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water to reach 1 mg/ml
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
WB (1:500 - 1:5000)
IHC (1:100 - 1:500)
Research areas Apoptosis,Neurology,Signal transduction
Print datasheet

Netrin receptor UNC5B antibody

Newsletter Receive news, promotions and offers in your e-mail box