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Musashi1 (Msi1) antibody

Gene name: MSI1
Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells.Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia.It may play a role in the pathogenesis of various neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play be an vital role in the development of several types of carcinoma such as human hepatoma, and may be a useful molecular marker for tumor detection.

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Ref : 00029084

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Product Code pab50511
Immunogen Reacts with residues 5-21 [APQPGLASPDSPHDPCK] of the human, mouse and rat Musashi 1 protein.
Target Specificity Reacts with Musashi1 from human, mouse and rat.
Name Musashi1 (Msi1)
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Immunohistochemistry, IHC - Paraffin sections
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC-P: 1:10-1:2000
- IHC: 1:10-1:2000
Research areas Neurology
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IHC: Musashi1 (Msi1) antibody<br/>(pab50511)<br/>Anti-Msi1 antibody IHC staining of human neural rosettes (green). Nuclei are counterstained blue (DAPI). Cells were fixed with 4 percent PFA. No antigen retrieval was done. Antibody pab50511 dilution 1:1000

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