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MTH1 antibody

7,8-dihydro-8-oxoguanine triphosphatase
2-hydroxy-dATP diphosphatase
Nucleoside diphosphate-linked moiety X motif 1, Nudix motif 1
Gene name: NUDT1, MTH1
MTH1 (human MutT Homolog 1) is an oxidized purine nucleoside triphosphatase enzyme that belongs to the Nudix hydrolase family and it acts as major mammalian detoxifier of the oxidized DNA precursor, 8-oxo-dGTP thereby exerting antimutagenic effects and suppressing cell dysfunction/death induced by oxidative stress.

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Ref : 00024774

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Product Code pab50073
Immunogen Synthetic peptide derived from the Cter domain of human MTH1 conjugated to KLH
Target Specificity Reacts with human, mouse and rat MTH1.
Name MTH1
Uniprot ID P36639
Gene ID 4521
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1.1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.05%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
WB 1:500
IHC 1:200
ICC/IF 1:50-1:200
Research areas Cancer,Nuclear signaling
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WB: MTH1 antibody<br/>(pab50073)<br/>Anti- MTH1 antibody WB staining of indicated cell lines

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