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Metabotropic Glutamate Receptor 2/3 antibody

Metabotropic glutamate receptor 2, mGluR2
Gene name: GRM2, Gprc1b, Mglur2
Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

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Ref : 00029085

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Product Code pab50514
Immunogen Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein.
Target Specificity Reacts with rat mGluR2/3. Predicted react to human and mouse.
Name Metabotropic Glutamate Receptor 2/3 (mGluR2/3)
Uniprot ID P31421
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Rat
Labelling None
Appearance Liquid
Form Purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, IHC - Paraffin sections
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC (1:10 - 1:2000)
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WB - Metabotropic Glutamate Receptor 2/3 antibody<br/>Anti-mGluR2/3 antibody WB staining of rat brain.

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