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MAPK3 / ERK1 (aa350-400) antibody

Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3
Extracellular signal-regulated kinase 1, ERK-1
Insulin-stimulated MAP2 kinase
MAP kinase isoform p44, p44-MAPK
Microtubule-associated protein 2 kinase
Gene name: MAPK3, ERK1, PRKM3
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

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Ref : 00024290

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Product Code pab74613
Immunogen Synthetic peptide from human MAPK3 / ERK1.
Target Specificity Reacts with human MAPK3 / ERK1.
Name MAPK3 / ERK1
Uniprot ID P27361
Gene ID 5595
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Purified (protein G)
Constituents PBS, 0.2% gelatin
Preservatives NaN3 0.05%
Storage Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
Applications Western Blot, IHC - Paraffin sections
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (10 µg/ml), WB (1 - 3 µg/ml)
Research areas Autophagy
Print datasheet

IHC : MAPK3 / ERK1 (aa350-400) antibody<br/>(pab74613)<br/>Anti-MAPK3 / ERK1 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74613 concentra

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