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MAPK3 / ERK1 (3C9) antibody

Mitogen-activated protein kinase 3, MAP kinase 3, MAPK 3
ERT2
Extracellular signal-regulated kinase 1, ERK-1
Insulin-stimulated MAP2 kinase
MAP kinase isoform p44, p44-MAPK
Microtubule-associated protein 2 kinase
p44-ERK1
Gene name: MAPK3, ERK1, PRKM3
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

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€410.00
Available
Ref : 00027598

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Product Code mab71055
Clone 3C9
Immunogen Human MAPK3 (AAH13992, 279 a.a. ~ 379 a.a) partial recombinant protein with GST tag.
Target Specificity Reacts with human MAPK3 / ERK1.
Name MAPK3 / ERK1
Uniprot ID P27361
Gene ID 5595
Print datasheet
Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG2a / Kappa
Produced in Mouse
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 0.39 mg/ml
Form Purified (protein A)
Constituents PBS, pH 7.2
Preservatives None
Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, Immunofluorescence, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IF (25 µg/ml),
IHC-P (10 µg/ml),
WB (1:500 - 1:1000)
Research areas Autophagy
Print datasheet

IHC : MAPK3 / ERK1 (3C9) antibody<br/>(mab71055)<br/>Anti-MAPK3 / ERK1 antibody IHC of human vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 µg/ml.

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