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MAPK1 / ERK (C-Terminus) antibody

Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1
Extracellular signal-regulated kinase 2, ERK-2
MAP kinase isoform p42, p42-MAPK
Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2
Gene name: MAPK1, ERK2, PRKM1, PRKM2
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors.

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Ref : 00025710

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Product Code pab74898
Immunogen Synthetic peptide derived from C-Terminus of rat MAPK1 / ERK.
Target Specificity Reacts with the C-terminus part of rat MAPK1 / ERK. Cross reacts with human and mouse protein.
Name MAPK1 / ERK
Uniprot ID P28482
Gene ID 5594
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Form Purified
Constituents PBS, pH 7.2, 50% glycerol, 0.1% gelatin
Preservatives 0.09% NaN3
Storage +4°C or -20°C, Avoid repeated freezing and thawing.
Applications Western Blot, IHC - Paraffin sections, Immunoprecipitation
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC - P (1:50)
Research areas Autophagy,Kinases and phosphatases
Print datasheet

IHC : MAPK1 / ERK (C-Terminus) antibody<br/>(pab74898)<br/>Anti-MAPK1 / ERK antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab74898 dilution 1:50.

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