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MAPK1 / ERK antibody

Mitogen-activated protein kinase 1, MAP kinase 1, MAPK 1
Extracellular signal-regulated kinase 2, ERK-2
MAP kinase isoform p42, p42-MAPK
Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2
Gene name: MAPK1, ERK2, PRKM1, PRKM2
erine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors

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Ref : 00025980

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Product Code pab75168
Immunogen Recombinant human MAPK1 protein
Target Specificity Reacts with human MAPK1 / ERK. Cross reacts with mouse and rat protein.
Name MAPK1 / ERK
Uniprot ID P28482
Gene ID 5594
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Purified
Constituents PBS, pH 7.4
Preservatives 0.02% NaN3
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Applications Western Blot, IHC - Paraffin sections
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC - P (5 µg/ml),
WB (1:1000 - 1:2000)
Research areas Autophagy,Kinases and phosphatases
Print datasheet

IHC : MAPK1 / ERK antibody<br/>(pab75168)<br/>Anti-MAPK1 / ERK2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 µg/ml.

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