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Maf protein antibody

Proto-oncogene c-Maf
V-maf musculoaponeurotic fibrosarcoma oncogene homolog
Gene name : MAF
Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

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Product Code pab0007
Immunogen Maf-GST fusion protein
Target Specificity Reacts with human 47 kDa Maf protein derived from a transfected CEFcell line.
Name Transcription factor Maf
Uniprot ID O75444
Gene ID NP_001026974.1
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA, Electron microscopy
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/50 to 1/500
- WB : 1/200 to 1/5 000
Useful for electrophoretic mobility shift assay (EMSA)
Research areas Cancer,Immunology,Nuclear signaling
Print datasheet
- Vial E. et al. Transcriptional control of SPArc by v-jun and other members of the AP1 family of ranscription factors. Oncogene, 2000, 19,5020-5029.

Maf protein antibody

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