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Inward rectifier potassium channel 2 (KCNJ2) antibody

Cardiac inward rectifier potassium channel
Inward rectifier K(+) channel Kir2.1 (IRK-1), (hIRK1)
Potassium channel, inwardly rectifying subfamily J member 2
Gene name : KCNJ2, IRK1
Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

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Product Code pab0293
Immunogen Synthetic peptide derived from Nter domain of KCNJ2 protein
Target Specificity Reacts with human KCNJ2 protein. Cross reacts with protein from mouse, rat and several other species
Name Inward rectifier potassium channel 2 (KCNJ2)
Uniprot ID P63252
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat
Labelling None
Appearance Lyophilized powder
Form Antiserum
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC (1:50 - 1:200)
WB (1:200 - 1:2000)
Research areas Ion channels,Neurology,Signal transduction
Print datasheet

ICC : KCNJ2 antibody<br/>(pab0293)<br/>Anti-KCNJ2 antibody ICC staining (green) of PC12 cells. Cells membranes are stained in red and nuclei in blue (DAPI)

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