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Hypoxia inducible factor-1 beta (HIF-1 beta) antibody

Aryl hydrocarbon receptor nuclear translocator
(ARNT protein)
Class E basic helix-loop-helix protein 2 (bHLHe2)
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta (HIF-1-beta), (HIF1-beta)
Gene name: ARNT, BHLHE2
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

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Ref : 00024780

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Product Code pab50017
Immunogen Fusion protein to human HIF-1 beta
Target Specificity Reacts with human HIF 1 beta /ARNT. Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.
Name Hypoxia-inducible factor 1-beta
Uniprot ID P27540
Gene ID 405
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse, Rat, Sheep, Bovine, Ferret
Labelling None
Appearance Liquid
Form Antiserum
Preservatives NaN3 0.02%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Immunohistochemistry, Immunoprecipitation, Chromatin IP
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP 1:10-1:500
ICC/IF (Negative),
IHC 1:150,
IP 1:10-1:500,
WB 1:2000
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IHC : HIF-1 beta antibody<br/>(pab50017)<br/>Anti- HIF-1 beta antibody IHC staining of skin epidermis.

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