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Hypoxia inducible factor-1 alpha antibody (H1alpha 67-7)

Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha)
ARNT-interacting protein
Basic-helix-loop-helix-PAS protein MOP1
Class E basic helix-loop-helix protein 78 (bHLHe78)
Member of PAS protein 1
PAS domain-containing protein 8
Gene name: HIF1A, BHLHE78, MOP1, PASD8
HIF-1 is a nuclear protein involved in mammalian oxygen homeostasis. This occurs as a posttranslational modification by prolyl hydroxylation. HIF-1 is a heterodimer composed of HIF-1 alpha and HIF-1 beta subunits. Both subunits are constantly translated.

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Ref : 00028932

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Product Code mab50062
Clone H1alpha 67-7
Immunogen Fusion protein containing amino acids 432-528 of human HIF-1 alpha
Target Specificity Reacts with human and monkeys HIF-1 alpha.
Name Hypoxia-inducible factor 1-alpha
Uniprot ID Q16665
Gene ID 3091
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Product type Primary antibodies
Clonality Monoclonal antibody
Isotype IgG2b
Produced in Mouse
Species Human, Monkey
Labelling None
Appearance Liquid
Conc. / Activity 1.5 mg/ml
Form Purified (protein G)
Constituents PBS
Preservatives NaN3 0.05%
Storage Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
-WB 1:500 -1:1000
Research areas Angiogenesis,Cancer,Developmental biology,Hypoxia,Nuclear signaling
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WB : HIF1-alpha antibody (H1alpha 67-7)<br/>(mab50062)<br/>Anti- HIF1-alpha antibody WB staining of HIF-1 alpha in (1) Cos7 CoCl2 treated cells and (2)untreated cells.

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