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HMGB1 (mono methyl K42) antibody

High mobility group protein B1
High mobility group protein 1, HMG-1
Gene name: HMGB1, HMG1
RP11-550P23.1, HMG3, SBP-1
HMGB1 is a DAMP involved in innate immune response. It is secreted by activated dendritic cells, macrophages and necrotic cells.

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Price From: €158.00
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Ref : 00013199

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Product Code pab0219
Immunogen Synthetic peptide derived from N terminal region of HMGB1, containing mono-methyl at K42
Target Specificity Reacts with HMGB1 methylated on Lysine 42 from human neutrophils. Not tested in other species. May cross react with a wide range of species due to sequence homology.
Name HMGB1 mono-methyl K42
Uniprot ID P09429
Gene ID 3146
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC 1:100 - 1:1000
WB 1:200
Research areas Chromatin,Immunology,Innate Immunity,Post translational modifications
Print datasheet
ichiaki Ito et al. Post-translational Methylation of High Mobility Group Box 1 (HMGB1) Causes Its ytoplasmic Localization in Neutrophils.June 1, 2007 The Journal of Biological Chemistry, 282, 16336-16344.

HMGB1 (mono methyl K42) antibody

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