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Glucose-6-phosphate isomerase (GPI) antibody

Autocrine motility factor (AMF)
Neuroleukin (NLK)
Phosphoglucose isomerase (PGI)
Phosphohexose isomerase (PHI)
Sperm antigen 36 (SA-36)
Gene name: GPI
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. Homodimer in the catalytically active form, monomer in the secreted form.

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Product Code pab0541
Immunogen Synthetic peptide derived from an internal domain of GPI
Target Specificity Reacts with human 65 kDa NLK protein. Cross reacts with proteins from mouse, rat and many other species due to sequence homology.
Name Glucose-6-phosphate isomerase (GPI)
Uniprot ID P06744
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/200 to 1/1 000
- WB : 1/500 to 1/5 000
Research areas Angiogenesis,Cancer,Cell biology,Neurology
Print datasheet
- Candler P.M. et al. Post-streptococcal opsoclonus-myoclonus syndrome associated with anti-neuroleukin antibodies. J Neurol Neurosurg Psychiatry 2006;77:507-512.

Glucose-6-phosphate isomerase (GPI) antibody

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