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Ganglioside-OacGD3 antibody (7H2)

Useful for monitoring gangliosides in ELISA, TLC and immunoblotting.

If you want to order offline

orders@covalab.com - tel: +33 (0) 437 654 230 - fax: +33 (0) 437 289 416

Price From: €158.00

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Ref : 00012723

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Product Code	mab0015
Clone	7H2
Immunogen	Ganglioside-OAcGD3
Target Specificity	Reacts with OAcGD3 ganglioside : OAcNeuAc alpha 2-8NeuAc alpha 2-3Gal beta 1-4Glc beta 1-1Cer.
Name	Ganglioside-OAcGD3

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Product type	Primary antibodies
Clonality	Monoclonal antibody
Isotype	IgG3 / Kappa
Produced in	Mouse
Species	All Species
Labelling	None
Appearance	Lyophilized powder
Form	Cell culture supernatant
Preservatives	None
Recommendations	Must be reconstituted in distilled water.
Storage	Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Applications	ELISA, Thin-layer chromatography
Working dilutions	Optimal dilution should be determined by the end user. The following are guidelines only : - ELISA : 1/5 to 1/50 - TLC : 1/5 to 1/20
Research areas	Cancer,Neurology,Signal transduction

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Cerato E. et al. Variable region gene segments of nine monoclonal antibodies specific todisialogangliosides (GD2, GD3) and their O-acetylated derivatives. Hybridoma (1997), 16(4),307-316.

Thomas C.P. et al. Gangliosides protect human melanoma cells from ionizing radiationinduced clonogenic cell death. Glycoconj. J. (1996), 13(3), 377-384.

Zebda N. et al. Deficiency of ganglioside biosynthesis in metastatic human melanoma cells: relevance of CMP-NeuAc:LacCer alpha 2-3 sialyltransferase (GM3 synthase). FEBS Letters (1995), 362(2), 161-164.

Portoukalian J. et al. Shedding of GD2 ganglioside in patients with retinoblastoma. Int. J.Cancer (1993), 53(6), 948-951.