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G protein-activated inward rectifier potassium channel 1 (GIRK-1) antibody

Inward rectifier K(+) channel Kir3.1
Potassium channel, inwardly rectifying subfamily J member 3
Gene name : KCNJ3, GIRK1
This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

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Price From: €202.00
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Product Code pab0322
Immunogen Synthetic peptide derived from Cter domain of GIRK-1 protein
Target Specificity Reacts with human 56 kDa GIRK-1 protein. Cross reacts with protein from mouse, rat and other species due to sequence homology.
Name G protein-activated inward rectifier potassium channel 1 (GIRK-1)
Uniprot ID P48549
Gene ID 3760
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunofluorescence, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IF 1:200 - 1:1000
WB 1:500 - 1:5000
Research areas Cardiac and vascular biomarkers,Ion channels,Neurology,Signal transduction
Print datasheet

G protein-activated inward rectifier potassium channel 1 (GIRK-1) antibody

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