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Fibrinogen antibody

Human fibrinogen is a complex ~340kD hetero-hexameric (di-trimeric) glycoprotein consisting of 3 pairs of alpha, beta and gamma chains linked by a series of 29 disulphide bonds. The six chains are arranged in such a way that all the N-Terminal ends adjoin to form a central with two trimeric coiled coil structures connecting to outer D domains. Fibrinogen plays an important role in the coagulation process with the D and E domains interacting via the C-Terminal ends of the alpha chains during fibrin clot cross-linking.

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Ref : 00024235

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Product Code pab74558
Immunogen Human Fibrinogen purified from plasma.
Target Specificity Reacts with human Fibrinogen. Cross reacts with mouse and rat protein. This antibody shows minimal cross-reactivity with related serum proteins
Name Fibrinogen
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Sheep
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 5 mg/ml
Form Purified (protein G)
Constituents PBS, pH 7.4
Preservatives NaN3 0.09%
Storage +4°C or -20°C, Avoid repeated freezing and thawing. Store undiluted.
Applications IHC - Paraffin sections, IHC - Frozen section, Immunofluorescence, ELISA
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
ELISA (1:50 - 1:100),
IHC-P (5 µg/ml)
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IHC - Fibrinogen antibody<br/>(pab74558)<br/>Anti-Fibrinogen antibody IHC of human placenta.<br/>Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.<br/>Antibody concentration 5 µg/ml.

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