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Fascin phospho S39 (FSCN1/pS39) antibody

55 kDa actin-bundling protein
Singed-like protein
p55
Gene name: FSCN1, FAN1, HSN, SNL
Phospho fascin
Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Phosphorylation on Ser-39 inhibits the actin-binding ability of fascin.

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Product Code pab0636
Immunogen Synthetic peptide derived from Nter domain of human FSCN1 containing phosphorserine at position 39
Target Specificity Reacts with 50 kDa FSCN1 with a phosphorylation at Serine 39. May cross react with FSCN1 phospho-proteins from rat, mouse and other species due to homology sequences.
Name Fascin phospho S39 (FSCN1/pS39)
Uniprot ID Q16658
Gene ID 6624
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Form Antiserum
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, Immunocytochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC (1:100 - 1:1000)
WB (1:500 - 1:2000)
Research areas Cell biology,Signal transduction
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Fascin phospho S39 (FSCN1/pS39) antibody

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