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F12 / Factor XII antibody

F12, Coagulation factor xii, F12 deficiency, Factor XII, Factor XII deficiency, HAE3, HAEX, HAF, Hageman factor
Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.

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Ref : 00028675

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Product Code pab75326
Immunogen Activated human Factor XII (F XIIa) purified from plasma.
Target Specificity Reacts with human F12 / Factor XII. Specific for Factor XII as demonstrated by immunodiffusion. A single precipitin arc was obtained with normal plasma and no reaction was observed with F. XII-deficient plasma.
Name F12 / Factor XII
Uniprot ID P00748
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Product type Primary antibodies
Clonality Polyclonal antibody
Isotype IgG
Produced in Goat
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Purified
Constituents 10 mM HEPES, pH 7.4, 0.15 M NaCl, 50% glycerol.
Preservatives None
Storage Long term: -20°C, Short term: +4°C. Avoid repeat freeze-thaw cycles.
Applications IHC - Paraffin sections, ELISA, Immunoprecipitation
Working dilutions IHC-P (5 µg/ml)
Research areas Angiogenesis,Cardiac and vascular biomarkers
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IHC : F12 / Factor XII antibody<br/>(pab75326)<br/>Anti-F12 / Factor XII antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 µg/ml.

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