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Eukaryotic translation initiation factor 3 subunit E (eIF3e) (C Terminus) antibody

Eukaryotic translation initiation factor 3 subunit 6
Viral integration site protein INT-6 homolog
eIF-3 p48
Gene name : EIF3E, EIF3S6, INT6
Belongs to the eIF-3 subunit E family. Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.

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Product Code pab0855-P
Immunogen Synthetic peptide derived from C terminal part of human eIF3e protein
Target Specificity Reacts with human eIF3e protein.
Name Eukaryotic translation initiation factor 3 subunit E (eIF3e)
Uniprot ID P60228
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunoprecipitation
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only :
- IP : 1/100 to 1/1000
- WB: 1/500 to 1/2000
Research areas Cell metabolism,Epigenetic
Print datasheet
- Neusiedler J, Mocquet V, Limousin T, Ohlmann T, Morris C, Jalinot P. INT6 interacts with MIF4GD/SLIP1 and is necessary for efficient histone mRNA translation. RNA. 2012 Jun;18(6):1163-77.

- Morris C, Tomimatsu N, Richard DJ, Cluet D, Burma S, Khanna KK, Jalinot P. INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells. Cancer Res. 2012 Apr 15;72(8):2006-16.

- Morris C, Wittmann J, Jäck HM, Jalinot P. Human INT6/eIF3e is required for nonsense-mediated mRNA decay. EMBO Rep. 2007 Jun;8(6):596-602.

- Morris-Desbois C, Réty S, Ferro M, Garin J, Jalinot P. The human protein HSPC021 interacts with Int-6 and is associated with eukaryotic translation initiation factor 3. J Biol Chem. 2001 Dec 7;276(49):45988-95

- Morris-Desbois C, Bochard V, Reynaud C, Jalinot P. Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies. J Cell Sci. 1999 Oct;112 ( Pt 19):3331-42.

Eukaryotic translation initiation factor 3 subunit E (eIF3e) (C Terminus) antibody

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