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CD16 antibody (NKP.15)
Low affinity immunoglobulin gamma Fc region receptor III-A/III-B
CD16a
CD16b
FCGR3A / FCGR3B
Gene : CD16a / CD16b
CD16a
CD16b
FCGR3A / FCGR3B
Gene : CD16a / CD16b
As low as
€350.00
In stock
Ref
00124725
CD16 antibody (NKP.15)
| ID Covalab | mab0292-p |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | NKP.15 |
| Isotype | IgG1 kappa |
| Raised in | Mouse |
| Immunogen | Human Large granular lymphocytic (LGL) |
| Activity cross reaction | The antibody recognizes a 50 to 65 kilodaltons (kDa) antigen present on human NK lymphocytes that is the IgG Fc receptor III. |
| Species | Human |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | CD16, also known as FcγRIII, is a low-affinity receptor for the Fc region of IgG antibodies, found on natural killer (NK) cells, neutrophils, and macrophages. It plays a key role in antibody-dependent cellular cytotoxicity (ADCC). CD16 exists in two isoforms: CD16a (membrane-bound) and CD16b (GPI-anchored). |
| Uniprot ID | P08637 / O75015 |
| Applications | FC, ICC |
| Working dilutions | Optimal dilution should be determined by the end user. The following instructions are only guidelines: FC: 1:1000 |
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