Alpha-Fetoprotein antibody [Biotin] (AFP-01)

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Alpha-fetoprotein (AFP) is present in fetal plasma, and it binds e.g. copper, nickel, and bilirubin. Measuring of alpha-fetoprotein level in amniotic fluid can reveal severe fetal defects. In adults, elevated AFP concentrations in the plasma can indicate hepatocellular carcinoma or teratoblastoma. In some individuals, hereditary persistance of alpha-fetoprotein can be observed without any obvious pathology.
More Information
ID Covalab mab21345
Product type Primary antibodies
Clonality Monoclonal antibody
Clone AFP-01
Isotype IgG1
Raised in Mouse
Immunogen Purified alpha-Fetoprotein
Activity cross reaction Human
Species Hu
Labelling Biotin
Form Purified
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze.
Target alpha-Fetoprotein
Uniprot ID P02771
Gene ID 174
Applications ELISA, ICC, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
WB : Recommended dilution: 1-2 μg/ml; non-reducing conditions. Interaction of the antibody AFP-01 with AFP is dependent on the presence of calcium ions (strongly inhibited by chelating agents). Such characteristics of the antibody can be exploited for immunoaffinity purification of APF under mild elution conditions.
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