C5aR2 antibody (1D9-M12)

C5a anaphylatoxin chemotactic receptor 2
Complement component 5a receptor 2
G-protein coupled receptor 77
Gene name: C5AR2, C5L2, GPR77
As low as €388.40
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00118973
C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin). It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances. Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.
More Information
ID Covalab mab21319
Product type Primary antibodies
Clonality Monoclonal antibody
Clone 1D9-M12
Isotype IgG2a kappa
Raised in Mouse
Immunogen The mouse monoclonal antibody 1D9-M12 recognizes an extracellular epitope on C5aR2 (C5L2), a C5a complement receptor, which is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g. in mast cells, astrocytes, or macrophages.
Activity cross reaction L1.2 cells transfected with human C5aR2
Species Hu
Labelling None
Form Purified (protein A)
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label.
Target C5aR2
Uniprot ID Q9P296
Gene ID 27202
Applications FC, WB
Working dilutions Optimal dilution should be determined by the end user.
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