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Nucleolin K88ac antibody
Protein C23
Gene name : NCL
acetylated Nucleolin, Nucleolin acetyl-lysine 88, NCL-K88ac
Gene name : NCL
acetylated Nucleolin, Nucleolin acetyl-lysine 88, NCL-K88ac
As low as
€294.00
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00106708
Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
| ID Covalab | pab0967-P |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic acetylated peptide surrounding Lysine 88 of human Nucleolin |
| Activity cross reaction | Reacts with Nucleolin with acetylated lysine 88 from human and mouse |
| Species | Hu, Ms |
| Labelling | None |
| Form | Purified (protein A) |
| Preservative | None |
| Storage instructions | Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Nucleolin K88ac |
| Uniprot ID | P19338 |
| Gene ID | 4691 |
| Applications | IF, IP, WB |
| Working dilutions | Optimal dilutions should be determined by the end user. The following are guidelines only: - WB : 1/100 to 1/500 - IF: 1/100 to 1/500 |
| Publication | * I Ugrinova et al. Nucleolin Interacts and Co-Localizes with Components of Pre-Catalytic Spliceosome Complexes. Sci, 2019 * Das S et al. Characterization of nucleolin K88 acetylation defines a new pool of nucleolin colocalizing with pre-mRNA splicing factors. FEBS Lett. 2013 Mar 1:587(5):417-24. |
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