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Seleno-Glutathione Peroxidase 4 (GPx-4) antibody
Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (PHGPx)
Glutathione peroxidase 4 (GPx-4) (GSHPx-4)
Gene name : GPX4
Glutathione peroxidase 4 (GPx-4) (GSHPx-4)
Gene name : GPX4
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€278.30
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00013420
otects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage.
ongs to the glutathione peroxidase family.
ongs to the glutathione peroxidase family.
| ID Covalab | pab0196 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide derived from N terminal domain of Seleno-glutathione peroxidases (GPx-4) |
| Activity cross reaction | Reacts with human Seleno-glutathione peroxidases (GPx-4). Cross reacts with mouse and rat proteins. |
| Species | Hu |
| Labelling | None |
| Form | Antiserum |
| Preservative | None |
| Storage instructions | Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt. |
| Target | Seleno-Glutathione Peroxidase 4 (GPx-4) |
| Uniprot ID | P36969 |
| Applications | ELISA, FC, IHC, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - FC : 1/100 - IHC : 1/100 to 1/1 000 - WB : 1/200 |
| Publication | * Januel C et al. Biochim Biophys Acta. 2006 Oct,1761(10):1228-34. * Ran Q et al. J Biol Chem. 2004 Dec 31,279(53):55137-46. * Véricel E et al. Diabetes. 2004 Apr,53(4):1046-51. (WB, Hu) |
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