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Octamer-binding protein 4 (Oct-4) antibody
POU domain, class 5, transcription factor 1
Octamer-binding protein 3 (Oct-3)
Octamer-binding protein 4 (Oct-4)
Octamer-binding transcription factor 3 (OTF-3)
Gene name: POU5F1, OCT3, OCT4, OTF3
Octamer-binding protein 3 (Oct-3)
Octamer-binding protein 4 (Oct-4)
Octamer-binding transcription factor 3 (OTF-3)
Gene name: POU5F1, OCT3, OCT4, OTF3
As low as
€480.40
In stock
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00030678
Stem cells are crucial ingredients in the progressive restriction of cellular developmental capacity during mammalian embryogenesis. Until recently, only embryonic stem cells (ESC)had been shown to exhibit the potential to differentiate into cells of the all three germ layers. However, adult stem cells (ASC) can regain pluripotency (potential to differentiate into various lineages) if transferred from one stem-cell microenvironment into another.The transcription factor OCT4, expressed in ESCs and germ cells, is strongly implicated in the process of maintaining as well as regaining stem-cell pluripotency and functions as a key regulator of mammalian germline development.
| ID Covalab | pab50208 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Polyclonal antibody |
| Raised in | Rabbit |
| Immunogen | Synthetic peptide made to an internal portion of the human OCT4 protein sequence (between residues 100-200) |
| Activity cross reaction | Reacts with Oct-4 protein from human, mouse, rat and primate. Predicted to cross react with bovine (93%), feline (93%), porcine (93%). |
| Species | Hu, Mk, Ms |
| Labelling | None |
| Form | Purified |
| Preservative | NaN3 0.05% |
| Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
| Target | Octamer-binding protein 4 (Oct-4) |
| Uniprot ID | Q01860 |
| Applications | FC, ICC, IF, WB |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: - WB : 2 µg/ml - FC: 1:50-1:200 -ICC/IF; 1:50-1:200 |
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