Histone H3 citrulline R2 + R8 + R17 antibody

Histone H3.3C
Gene name: H3F3C
As low as €294.00
In stock
Ref
00013174
Belongs to the histone H3 family.
More Information
ID Covalab pab0208-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide derived from Nter domain of human Histone H3 containing Citrulline at position 2-8-17
Activity cross reaction Reacts with human Histone H3 Citrulline at the 3 positions: 2, 8 and 17. Reacts with mono or di H3-Cit. Not tested in other species. May cross reacts with other species due to sequence homology.
Species Hu
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Histone H3 citrulline R2 + R8 + R17
Applications ChIP, ELISA, IHC, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC (1:200- 1:1000)
WB (1:5000 - 1:50000)
Publication Raijmakers R et al. Methylation of arginine residues interferes with citrullination by peptidylarginine deiminases in vitro. J Mol Biol. 2007 Apr 6,367(4):1118-29.
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