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Oval Cell Marker antibody (OC2-2A6)
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€480.40
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00099048
Facultative liver stem cell activation was originally described in the rat, where chemical damage and partial hepatectomy caused the emergence of a new cell type, the oval cell. These cells are thought to be bipotential progenitors capable of yielding both hepatocytes and bile ducts (1). To properly determine the molecular regulation of the progenitor process, appropriate markers are needed to identify and isolate cells that emerge during the oval cell response.
| ID Covalab | mab50885 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | OC2-2A6 |
| Isotype | IgG1 |
| Raised in | Rat |
| Immunogen | Nonparenchymal cells from DDC-treated mice to induce the oval cell response. |
| Activity cross reaction | Reacts with mouse Oval Cell Marker (for proliferating hepatic periductal cells). |
| Species | Ms |
| Labelling | None |
| Form | Cell culture supernatant |
| Preservative | NaN3 0.09% |
| Storage instructions | Store at 4°C. Do not freeze. |
| Target | Oval Cell Marker |
| Applications | FC, ICC, IF, IHC - F |
| Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only : - FC : 1/50 to 1/100 - IHC - F : 1/100 |
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