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Secretory phospholipase A2 receptor (PLA2R) peptide
Secretory phospholipase A2 receptor, PLA2R, PLA2-R
180 kDa secretory phospholipase A2 receptor
C-type lectin domain family 13 member C
M-type receptor
Gene name : PLA2R1, CLEC13C
180 kDa secretory phospholipase A2 receptor
C-type lectin domain family 13 member C
M-type receptor
Gene name : PLA2R1, CLEC13C
As low as
€249.30
In stock
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00096388
Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells.
| ID Covalab | pep0527 |
|---|---|
| Product type | Peptides |
| Target domain | C-terminal part |
| Activity cross reaction | This peptide blocks completely the immuno reactivity of the antibody pab0527 in WB or IHC by incubating the peptide with equivalent volume of antibody for 30 min at 37 °C. |
| Species | Hu |
| Labelling | None |
| Antibody / Antigen | pab0527 |
| Preservative | NaN3 0.02 % |
| Storage instructions | Shipment at 4°C. Upon arrival, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. |
| Target | PLA2R |
| Uniprot ID | Q13018 |
| Gene ID | 22925 |
| Description | ELISA, WB, IHC |
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