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CD146 antibody (P1H12) [PerCP]
Cell surface glycoprotein MUC18
Cell surface glycoprotein P1H12
Melanoma cell adhesion molecule
Melanoma-associated antigen A32
Melanoma-associated antigen MUC18
S-endo 1 endothelial-associated antigen
CD146
Gene name: MCAM, MUC18
Cell surface glycoprotein P1H12
Melanoma cell adhesion molecule
Melanoma-associated antigen A32
Melanoma-associated antigen MUC18
S-endo 1 endothelial-associated antigen
CD146
Gene name: MCAM, MUC18
As low as
€594.10
In stock
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00118592
CD146, also known as MCAM (melanoma cell adhesion molecule) or MUC18, is a heavily glycosylated transmembrane glycoprotein with more than 50% of the mass from carbohydrates. It is expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, activated T cells and activated keratinocytes, and on some cancer cells, especially melanoma. The presence of CD146 on circulating blood cells has been confined to the activated T cells rather than circulating endothelial cells. CD146 mediates heterophilic cell adhesion and regulates monocyte transendothelial migration.
| ID Covalab | mab21300 |
|---|---|
| Product type | Primary antibodies |
| Clonality | Monoclonal antibody |
| Clone | P1H12 |
| Isotype | IgG1 |
| Raised in | Mouse |
| Immunogen | The mouse monoclonal antibody P1H12 recognizes an extracellular epitope of CD146, a 118 kDa transmembrane glycoprotein expressed on epithelial and endothelial cells, fibroblasts, multipotent mesenchymal stromal cells, melanoma cells, activated T cells and activated keratinocytes. |
| Activity cross reaction | Cultured human umbilical cells |
| Species | Hu |
| Labelling | PerCP |
| Form | Purified (liquid chromatography) |
| Preservative | NaN3 15 mM |
| Storage instructions | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on the label. |
| Target | CD146 |
| Uniprot ID | P43121 |
| Gene ID | 4162 |
| Applications | FC |
| Working dilutions | Optimal dilution should be determined by the end user. |
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