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DSP / Desmoplakin (Internal) antibody

DSP, Apeg-1, Apeg-1 protein, Desmoplakin i, Desmoplakin II, DP, DPI, DPII
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

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Ref : 00023575

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Product Code pab74221
Immunogen Synthetic peptide C-QESVKQAHLRNEH from an internal region of human DSP / Desmoplakin (NP_004406.2). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Marmoset (100%), Monkey (92%), Mouse (92%)
Target Specificity Reacts with human DSP / Desmoplakin. Cross reacts with mouse and rat protein. This antibody is expected to recognize reported isoform I (NP_004406.2) only.
Name DSP / Desmoplakin
Accession Number P15924
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Goat
Species Human, Mouse, Rat
Labelling None
Appearance Liquid
Conc. / Activity 0.5 mg/ml
Form Antigen affinity purified
Constituents TBS, pH 7.3, BSA 0.5%
Preservatives NaN3 0.02%
Storage Store at -20°C. Minimize freezing and thawing.
Applications IHC - Paraffin sections, ELISA
Working dilutions ELISA (1:4000), IHC-P (3.75 µg/ml)
Research areas Cell biology,Cytoskeleton
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DSP / Desmoplakin (Internal) antibody<br/>(pab74221)<br/>Anti-DSP / Desmoplakin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 µg/ml.

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