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Desmoplakin antibody

250/210 kDa paraneoplastic pemphigus antigen
Gene name: DSP
Major high molecular weight protein of desmosomes. Involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes.

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Price From: €165.00
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Product Code pab0568-P
Immunogen Synthetic peptide derived from an internal domain of human DP
Target Specificity Reacts with human Desmoplakin I and II. Cross reacts with proteins from other species due to sequence homology.
Name Desmoplakin (DP)
Uniprot ID P15924
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/100 to 1/500
- WB : 1/500 to 1/5 000
Research areas Cell biology,Cytoskeleton
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Desmoplakin antibody

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