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Crystallin AB antibody

Heat shock protein beta-5 (HspB5)
Renal carcinoma antigen NY-REN-27
Rosenthal fiber component
Gene name: CRYAB, CRYA2
Crystallin AB (CryAB) is a developmentally regulated small heat shock protein known to protect cells from stress damage.It may also play an important role in the Golgi reorganization during cell division.CryAB is known to be associated with a number of neurodegenerative pathologies such as Alzheimer disease amd multiple sclerosis. As well, it has been found to be expressed in breast tumors of patients with shorter survival, suggesting that it may be a useful marker in identifying aggressive breast cancer.

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Ref : 00030389

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Product Code pab50222
Immunogen Synthetic peptide made to a C-terminal region of the human Crystallin AB protein (within residues 100-175)
Target Specificity Reacts with human and mouse CRYAB protein. May cross react with rat, sheep, rabbit, monkey, hamster, cow, and pig proteins (100% sequence homology).
Name Alpha-crystallin B chain
Uniprot ID P02511
Gene ID 1410
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse
Labelling None
Appearance Liquid
Conc. / Activity 0.9 mg/ml
Form Antigen affinity purified
Constituents Tris-citrate, phosphate, (pH 7-8) buffer
Preservatives NaN3 0.1%
Storage Store at 4°C. Do not freeze.
Antibody / Antigen pep50030
Applications Western Blot
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
WB 0.5-1 ug/ml
Research areas Cancer,Cell biology,Signal transduction
Print datasheet

WB : Crystallin AB antibody<br/>(pab50222)<br/>Anti-Crystallin AB antibody WB staining of  human skeletal muscle (Lane 1) and mouse skeletal muscle proteins (Lane 2)

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