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CLOCK antibody

Circadian locomoter output cycles protein kaput (hCLOCK)
Class E basic helix-loop-helix protein 8 (bHLHe8)
Gene name:CLOCK, BHLHE8, KIAA0334
Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior.

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Product Code pab50003
Immunogen Two synthetic peptides derived from mouse CLOCK conjugated to albumin.
Target Specificity Reacts with human and mouse 95 kDa CLOCK protein.
Name Circadian locomoter output cycles protein kaput (hCLOCK)
Uniprot ID O08785
Gene ID 9575
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human, Mouse
Labelling None
Appearance Liquid
Form Antiserum
Preservatives NaN3 0.05%
Storage Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Applications Western Blot, Chromatin IP
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ChIP 1:1 000
WB 1:1 000
Research areas Cell metabolism
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WB : CLOCK antibody <br/>(pab50003)<br/>Anti- CLOCK antibody WB staining of alpha CLOCK immunoprecipitated DNA (15, 10 and 5 ul of antisera added respectively to the 900 ul of sonicated chromatin sample in the ChIP assay.

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