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Charged multivesicular body protein 3 (CHMP3) antibody

Chromatin-modifying protein 3
Neuroendocrine differentiation factor (hVps24)
Gene name: CHMP3, CGI149, NEDF, VPS24
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.

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Price From: €165.00
Ref : 00014090

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Product Code pab0710-P
Immunogen Synthetic peptide derived from internal domain of human Vps24 protein
Target Specificity Reacts with human 25 kDa hVps24. May cross-react with protein from mouse, rat and other species due to sequence homology.
Name Charged multivesicular body protein 3
Uniprot ID Q9Y3E7
Gene ID 51652
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Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunohistochemistry, ELISA
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
- IHC : 10 µg/ml
Research areas Cell biology,Neurology,Signal transduction
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IHC-P : Charged multivesicular body protein 3 (CHMP3) antibody<br/>(pab0710-P)<br/>Anti-CHMP3 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody pab0710-

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