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Charged multivesicular body protein 2b (CHMP2b) antibody

Charged multivesicular body protein 2b
CHMP2.5
Chromatin-modifying protein 2b (CHMP2b)
Vacuolar protein sorting-associated protein 2-2 (Vps2-2), (hVps2-2)
Gene name : CHMP2B
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Belongs to the SNF7 family.

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Product Code pab0841-P
Immunogen Human CHMP2b recombinant protein tagged with MBP.
Target Specificity Reacts with human CHMP2b.
Name Charged multivesicular body protein 2b (CHMP2b)
Uniprot ID Q9UQN3
Gene ID 25978
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Lyophilized powder
Conc. / Activity 1 mg/ml
Form Purified (protein A)
Constituents Tris 0,1M, glycine 0,1M, sucrose 2%
Preservatives None
Recommendations Must be reconstituted in distilled water.
Storage Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Applications Western Blot, Immunofluorescence, ELISA
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB 1:200 - 1:5 000
IF 1:100 - 1:2 000
Research areas Neurology,Signal transduction,Synthesis and degradation,Vesicle trafficking
Print datasheet

Charged multivesicular body protein 2b (CHMP2b) antibody

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