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CD209 / DC-SIGN (Internal) antibody

CD209 antigen
C-type lectin domain family 4 member L
Dendritic cell-specific ICAM-3-grabbing non-integrin 1, DC-SIGN, DC-SIGN1, CDSIGN
Gene name: CD209, CLEC4L
Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

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€360.00
Available
Ref : 00016327

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Product Code pab70593
Immunogen Synthetic peptide from human CD209 / DC-SIGN.
Target Specificity Reacts with the center of human DC-DIGN
Name CD209 / DC-SIGN
Uniprot ID Q9NNX6
Gene ID 30835
Print datasheet
Product type Primary antibodies
Clonality Polyclonal antibody
Produced in Rabbit
Species Human
Labelling None
Appearance Liquid
Conc. / Activity 1 mg/ml
Form Antigen affinity purified
Constituents PBS
Preservatives NaN3 0.02%
Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Applications Western Blot, IHC - Paraffin sections
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (5 µg/ml), WB (1 - 2 µg/ml)
Research areas Innate Immunity
Print datasheet

IHC : CD209 / DC-SIGN (Internal) antibody<br/>(pab70593)<br/>Anti-CD209 / DC-SIGN antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 µg/ml.

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