CD49e antibody (SAM1)

Integrin alpha-5
CD49 antigen-like family member E
Fibronectin receptor subunit alpha
Integrin alpha-F
VLA-5
Gene name: CD49e
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00122151
CD49e (VLA5 alpha) is a type I transmembrane glycoprotein of the integrin alpha subclass (intergrin 5 alpha), expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells. It binds to RGD sequence in fibronectin and to neural adhesion molecule L1. CD49e interactions are important for maintaining the integrity of the endothelial monolayer, as well as it is involved in monocyte migration, T cell costimulation, regulation of cell survival, and other.
More Information
ID Covalab mab21341
Product type Primary antibodies
Clonality Monoclonal antibody
Clone SAM1
Isotype IgG2 beta
Raised in Mouse
Immunogen U937 cells
Activity cross reaction Non-human primates, Human
Species Hu
Labelling None
Form Purified
Preservative NaN3 15 mM
Storage instructions Store at 2-8°C. Do not freeze.
Target CD49e
Uniprot ID P08648
Gene ID ITGA5
Applications FC
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
FC (1-4 µg/ml)
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