Glu-alpha-Tubulin (Detyrosinated alpha-Tubulin) antibody

Detyrosinated alpha-Tubulin
Tubulin alpha-1A chain
Alpha-tubulin 3
Tubulin B-alpha-1
Tubulin alpha-3 chain
Gene name: TUBA1A, TUBA3
As low as $323.40
In stock
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00013594
Human alpha-Tubulin can be detyrosinated by the tubulin tyrosine carboxypeptidase (TTCP)
More Information
ID Covalab pab0201-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen A 10 residues synthetic peptide of Cter domain of human tubulin
Activity cross reaction Reacts with human, mouse and rat Glu-alpha-Tubulin (Detyrosinated alpha-tubulin). Does not cross react with alpha-tubulin.
Species Hu, Ms, Rat
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Lyophilized powder stable for a minimum of 2 years at -20°C.
Store reconstituted antibodies at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Glu-alpha-Tubulin
Uniprot ID Q71U36
Gene ID 7846
Applications ELISA, IHC, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC (1:50 - 1:200)
WB (1:500 - 1:2000)
Publication * Peris L et al. Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends. J Cell Biol. 2006;174 :839-49.
* Mialhe A. et al. Tubulin detyrosination is a frequent occurrence in breast cancers of poor prognosis. CancerRes. 2001 Jul 61: 5024-7.
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