Hypoxia inducible factor-1 beta (HIF-1 beta) antibody

Aryl hydrocarbon receptor nuclear translocator
(ARNT protein)
Class E basic helix-loop-helix protein 2 (bHLHe2)
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta (HIF-1-beta), (HIF1-beta)
Gene name: ARNT, BHLHE2
As low as $528.40
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00024780
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
More Information
ID Covalab pab50017
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Fusion protein to human HIF-1 beta
Activity cross reaction Reacts with human HIF 1 beta /ARNT. Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species.
Species Bov, Ft, Hu, Ms, Rat, Sh
Labelling None
Form Antiserum
Preservative NaN3 0.02%
Storage instructions Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Target Hypoxia-inducible factor 1-beta
Uniprot ID P27540
Gene ID 405
Applications ChIP, IHC, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only:
ChIP 1:10-1:500
ICC/IF (Negative),
IHC 1:150,
IP 1:10-1:500,
WB 1:2000
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