We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Hypoxia inducible factor-1 beta (HIF-1 beta) antibody
Aryl hydrocarbon receptor nuclear translocator
(ARNT protein)
Class E basic helix-loop-helix protein 2 (bHLHe2)
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta (HIF-1-beta), (HIF1-beta)
Gene name: ARNT, BHLHE2
(ARNT protein)
Class E basic helix-loop-helix protein 2 (bHLHe2)
Dioxin receptor, nuclear translocator
Hypoxia-inducible factor 1-beta (HIF-1-beta), (HIF1-beta)
Gene name: ARNT, BHLHE2
As low as
$528.40
In stock
Ref
00024780
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
ID Covalab | pab50017 |
---|---|
Product type | Primary antibodies |
Clonality | Polyclonal antibody |
Raised in | Rabbit |
Immunogen | Fusion protein to human HIF-1 beta |
Activity cross reaction | Reacts with human HIF 1 beta /ARNT. Cross reacts with proteins from bovine, sheep, mouse, rat and ferret. Not tested in other species. |
Species | Bov, Ft, Hu, Ms, Rat, Sh |
Labelling | None |
Form | Antiserum |
Preservative | NaN3 0.02% |
Storage instructions | Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles. |
Target | Hypoxia-inducible factor 1-beta |
Uniprot ID | P27540 |
Gene ID | 405 |
Applications | ChIP, IHC, IP, WB |
Working dilutions | Optimal dilution should be determined by the end user. The following are guidelines only: ChIP 1:10-1:500 ICC/IF (Negative), IHC 1:150, IP 1:10-1:500, WB 1:2000 |
Write Your Own Review