LANA2 antibody (CM-A807)

Kaposi's sarcoma-associated herpes virus LANA2
KSHV
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00096459
LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist.It is a nuclear protein associated with Kaposi's sarcoma-associated herpes virus (KSHV), or human herpes virus 8.It is found in abundance in the nuclei of cultured cells from KSHV-infected hematopoietic tissues, such as PEL (primary effusion lymphoma) and CD (multicentric Castleman's disease).It does not appear to be expressed in KS (Kaposi's sarcoma) lesions.
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ID Covalab mab50074
Product type Primary antibodies
Clonality Monoclonal antibody
Clone CM-A807
Isotype IgG1 / Kappa
Raised in Mouse
Immunogen Recombinant LANA2 fusion protein
Activity cross reaction Reacts with human and murin Kaposi's sarcoma-associated herpes virus (KSHV) ~66-70 kDa LANA2 protein and shows no cross-reactivity to cellular proteins.
Species HV
Labelling None
Form Purified (protein G)
Preservative None
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Latency-associated nuclear antigen 2 (LANA2)
Applications ELISA, IF, IHC, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/10 to1/2000
- IF : 2 to 4 µg/ml
- IP : 2 to 4 µg/ml
- WB : 2 to 4 µg/ml
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