MBD3 antibody

Methyl-CpG-binding domain protein 3
Methyl-CpG-binding protein MBD3
Gene name : MBD3
As low as $323.40
In stock
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00106921
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
More Information
ID Covalab pab0980-P
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide of derived from C terminal part of human MBD3.
Activity cross reaction Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology).
Species Ham, Hu, Mk, Ms, Rat
Labelling None
Form Purified (protein A)
Preservative None
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target MBD3
Uniprot ID O95983
Gene ID 53615
Applications ELISA, ICC, IF, WB
Working dilutions Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000
- ICC, IF: 1/200 to 1/1000
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