Park7 / DJ-1 antibody

Oncogene DJ1
Parkinson disease protein 7
Gene name: PARK7
As low as $528.40
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00099303
Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
More Information
ID Covalab pab50148
Product type Primary antibodies
Clonality Polyclonal antibody
Raised in Rabbit
Immunogen Synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1).
Activity cross reaction Reacts with human and mouse Protein DJ-1. May cross react with rat, bovine, Zebra fish, Golden hamster and chicken proteins (100% sequence homology).
Species Hu, Ms
Labelling None
Form Antiserum
Preservative None
Storage instructions Short term storage at +4°C.
For extended periods store in aliquots at -20°C.
Antibodies are guaranteed for 6 month from date of receipt.
Target Protein DJ-1
Uniprot ID Q99497
Gene ID 11315
Applications FA, ICC, IF, IP, WB
Working dilutions Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC 1:500
IP 1:200
WB 1:2 000
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